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Basic Research for Clinicians

Sample Size for Experimental Studies

Volume 1, Apr 2012

Padam Singh, MD, Gurgaon, India

An essential part of any medical research is to decide how many subjects need to be studied. A formal sample size calculation is a prerequisite to justify that the study
with this size is capable of answering the research questions. This article highlights the statistical principles involved in sample size calculation along with formulae
used in different situation illustrating with examples. The implications of deviations are also discussed.

Volume 1, Number 2, Page: 88-93

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